Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology

Epigenetic Regulation of the Non-Coding Genome: Opportunities for Immuno-Oncology

Blog Article

The contribution of the non-coding genome to disease and its therapeutic potential have been largely COCONUT FOOT CREME unexplored.Recently, several epigenetic drugs developed for cancer treatment have been described to mediate therapeutic effects through the reactivation of the expression of transposable elements in cancer cells.This event activates innate immunity-related pathways and promotes the generation of neoantigens in tumor Memorial Keychain Gift Box cells, improving the efficacy of immunotherapeutic treatments.This review focuses on the regulation of transposable elements by epigenetic inhibitors and its implications for immuno-oncology.